Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 14/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7475955 | 0.85 | HTT (0.55) | HTTPPARGTSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL7474325 | 0.83 | TSHR (0.65) | HTTSIRT1PPARGTSHRALDH1A1 | |
| SCHEMBL7476860 | 0.82 | TSHR (0.64) | HTTPPARGTSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL7473032 | 0.81 | HTT (0.52) | HTTPPARGTSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL7468634 | 0.80 | HTT (0.54) | HTTPPARGTSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL7472920 | 0.78 | TSHR (0.56) | HTTPPARGTSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL7473291 | 0.77 | TSHR (0.54) | HTTPPARGTSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL7471315 | 0.76 | ALDH1A1 (0.68) | HTTTSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL7472305 | 0.76 | TSHR (0.53) | HTTPPARGTSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL7477378 | 0.75 | SIRT1 (0.48) | HTTSIRT1PPARGTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |