Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 9/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | PGR | P06401 | 2/20 | 0.51 |
| ▸ | AR | P10275 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.49 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | IL5 | P05113 | 1/20 | 0.49 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | THPO | P40225 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Rofleponide SCHEMBL5506220 | 1.00 | NR3C1 (0.68) | NR3C1CYP3A4LMNAHIF1AHSD17B10 | |
| Rofleponide SCHEMBL7196822 | 1.00 | NR3C1 (0.68) | NR3C1CYP3A4LMNAHIF1AHSD17B10 | |
| Rofleponide SCHEMBL23803954 | 1.00 | NR3C1 (0.68) | NR3C1CYP3A4LMNAHIF1AHSD17B10 | |
| Rofleponide SCHEMBL8505525 | 1.00 | NR3C1 (0.68) | NR3C1CYP3A4LMNAHIF1AHSD17B10 | |
| Rofleponide SCHEMBL6449744 | 0.97 | NR3C1 (0.64) | NR3C1CYP3A4LMNAHIF1AHSD17B10 | |
| SCHEMBL8204804 | 0.93 | NR3C1 (0.67) | NR3C1CYP3A4LMNAHIF1AHSD17B10 | |
| SCHEMBL7081817 | 0.93 | NR3C1 (0.70) | NR3C1CYP3A4LMNAHIF1AHSD17B10 | |
| SCHEMBL8674574 | 0.93 | NR3C1 (0.70) | NR3C1CYP3A4LMNAHIF1AHSD17B10 | |
| SCHEMBL6323559 | 0.92 | NR3C1 (0.57) | NR3C1CYP3A4LMNAHIF1AHSD17B10 | |
| SCHEMBL8138913 | 0.92 | NR3C1 (0.66) | NR3C1CYP3A4LMNAHIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 6649 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260130899-A1 | METHOD OF TREATMENT FOR PREVENTION OF GLUCOCORTICOID TOXICITY AND/OR ENHANCEMENT OF MUSCLE REGENERATION VIA NEUTROPHIL ELASTASE INHIBITION | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2026-05-14 | — | — | US | claimed |
| US-12616654-B2 | Stainless steel can for pressurised metered dose inhalers | CHIESI FARMACEUTICI S.P.A. (IT) | 2026-05-05 | — | — | US | claimed |
| EP-4434588-B1 | AEROSOL DELIVERY DEVICE | PARI PHARMA GMBH (DE) | 2026-04-08 | — | — | EP | claimed |
| US-20260034056-A1 | PHARMACEUTICAL COMPOSITIONS FOR TREATING OCULAR DISEASES OR DISORDERS | ALCON INC (CH) | 2026-02-05 | — | — | US | claimed |
| EP-4656202-A1 | TREATMENT OF ATOPIC DERMATITIS WITH POLYETHYLENE GLYCOL-MODIFIED INTERLEUKIN 2, GLUCOCORTICOID AND HYALURONIC ACID | Xie, Yanhui (CN) | 2025-12-03 | — | — | EP | claimed |
| US-20250312274-A1 | A PHARMACEUTICAL FORMULATION FOR PRESSURISED METERED DOSE INHALER | CHIESI FARMACEUTICI S.P.A. (IT) | 2025-10-09 | — | — | US | claimed |
| US-20250302742-A1 | A PHARMACEUTICAL FORMULATION FOR PRESSURISED METERED DOSE INHALER | CHIESI FARMACEUTICI S.P.A. (IT) | 2025-10-02 | — | — | US | claimed |
| EP-4531920-A1 | A PHARMACEUTICAL FORMULATION FOR PRESSURISED METERED DOSE INHALER | Chiesi Farmaceutici S.p.A. (IT) | 2025-04-09 | — | — | EP | claimed |
| EP-4531922-A1 | A PHARMACEUTICAL FORMULATION FOR PRESSURISED METERED DOSE INHALER | Chiesi Farmaceutici S.p.A. (IT) | 2025-04-09 | — | — | EP | claimed |
| EP-4531921-A1 | A PHARMACEUTICAL FORMULATION FOR PRESSURISED METERED DOSE INHALER | Chiesi Farmaceutici S.p.A. (IT) | 2025-04-09 | — | — | EP | claimed |
| US-5874063-A | Pharmaceutical formulation | ASTRA AKTIEBOLAG (SE) | 1999-02-23 | — | — | US | claimed |
| WO-1999000134-A1 | NEW COMBINATION OF ANTIASTHMA MEDICAMENTS | ASTRA AKTIEBOLAG (PUBL) (SE) | 1999-01-07 | — | — | WO | claimed |
| CN-1186428-A | Process for the preparation of particles suitable for inhalation use | ASTRA AB (SE) | 1998-07-01 | — | — | CN | claimed |
| CN-1179721-A | Novel pharmaceutical formulations | ASTRA AB (SE) | 1998-04-22 | — | — | CN | claimed |
| EP-0820276-A1 | PROCESS FOR THE PREPARATION OF RESPIRABLE PARTICLES | Astra Aktiebolag (SE) | 1998-01-28 | — | — | EP | claimed |
| EP-0809501-A1 | NOVEL PHARMACEUTICAL FORMULATION | Astra Aktiebolag (SE) | 1997-12-03 | — | — | EP | claimed |
| EP-0809498-A1 | NOVEL PHARMACEUTICAL COMBINATION | Astra Aktiebolag (SE) | 1997-12-03 | — | — | EP | claimed |
| WO-1996032095-A1 | PROCESS FOR THE PREPARATION OF RESPIRABLE PARTICLES | ASTRA AKTIEBOLAG (SE) | 1996-10-17 | — | — | WO | claimed |
| WO-1996024359-A1 | NOVEL PHARMACEUTICAL FORMULATION | ASTRA AKTIEBOLAG (SE) | 1996-08-15 | — | — | WO | claimed |
| WO-1996024355-A1 | NOVEL PHARMACEUTICAL COMBINATION | ASTRA AKTIEBOLAG (SE) | 1996-08-15 | — | — | WO | claimed |