Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 15/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7471327 | 0.92 | TP53 (0.40) | TSHRHTTALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL7465291 | 0.92 | TSHR (0.46) | TSHRHTTALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL7470321 | 0.90 | NPFFR1 (0.36) | TSHRHTTALDH1A1TP53 | |
| SCHEMBL8599910 | 0.89 | GSK3B (0.42) | TP53PPARG | |
| Hydrochloric Acid SCHEMBL7462740 | 0.89 | NPFFR1 (0.36) | TSHRHTTALDH1A1TP53 | |
| SCHEMBL8603773 | 0.89 | PPARG (0.44) | TP53PPARG | |
| SCHEMBL7475653 | 0.89 | ALDH1A1 (0.42) | TSHRALDH1A1SMN1; SMN2TP53PPARG | |
| SCHEMBL8595844 | 0.88 | TSHR (0.45) | TSHRALDH1A1SMN1; SMN2TP53PPARG | |
| SCHEMBL8604494 | 0.88 | ALDH1A1 (0.43) | TSHRALDH1A1SMN1; SMN2TP53PPARG | |
| SCHEMBL8557727 | 0.88 | GSK3B (0.47) | TSHRALDH1A1SMN1; SMN2TP53PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-B1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO MCNEIL PHARM INC (US) | 2002-12-18 | — | — | EP | claimed |
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | claimed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | claimed |
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |