Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | ADK | P55263 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8602122 | 0.93 | TSHR (0.44) | GSK3BADKALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL8604494 | 0.92 | ALDH1A1 (0.43) | GSK3BADKALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL8595844 | 0.92 | TSHR (0.45) | ALDH1A1SMN1; SMN2TSHRTP53PPARG | |
| SCHEMBL8603773 | 0.90 | PPARG (0.44) | TP53PPARGLMNA | |
| SCHEMBL8554476 | 0.90 | TSHR (0.46) | ALDH1A1SMN1; SMN2TSHRTP53PTPN1 | |
| SCHEMBL7475653 | 0.90 | ALDH1A1 (0.42) | GSK3BADKALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL8604038 | 0.89 | TP53 (0.42) | GSK3BADKALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL8603405 | 0.89 | TSHR (0.42) | GSK3BADKALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL8556736 | 0.89 | SIRT2 (0.41) | ALDH1A1SMN1; SMN2TSHRTP53SIRT2 | |
| SCHEMBL7476790 | 0.88 | TSHR (0.45) | ALDH1A1SMN1; SMN2TSHRTP53PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5854242-A | Benzoxazine antimicrobial agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-12-29 | — | — | US | disclosed |
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| US-5696117-A | BACTERICIDE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-12-09 | — | — | US | disclosed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |