Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7474295 | 0.78 | TSHR (0.44) | MAPTKDM4EMEN1KMT2ALMNA | |
| SCHEMBL7477967 | 0.77 | NR1H2 (0.36) | RAB9ANPC1NR1H2NR1H3CRHR1 | |
| SCHEMBL7471708 | 0.74 | NR1H2 (0.38) | MAPTRAB9ASMN1; SMN2NPC1NR1H2 | |
| SCHEMBL6976971 | 0.72 | GAA (0.35) | MAPTKMT2ALMNAPOLBSMN1; SMN2 | |
| SCHEMBL7476369 | 0.71 | NR1H2 (0.43) | MAPTKDM4ERAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7526323 | 0.70 | PDE2A (0.34) | KDM4ERXFP1KMT2ALMNARAB9A | |
| SCHEMBL5726642 | 0.69 | PDE2A (0.33) | MAPTKDM4ERXFP1KMT2ALMNA | |
| SCHEMBL6073454 | 0.69 | PDE2A (0.33) | KDM4ERXFP1KMT2ALMNARAB9A | |
| SCHEMBL5727053 | 0.69 | PDE2A (0.33) | KDM4ERXFP1KMT2ALMNARAB9A | |
| SCHEMBL5726652 | 0.69 | PKM (0.34) | MAPTRXFP1RAB9ANPC1NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0922043-B1 | PESTICIDAL 3-(SUBSTITUTED PHENYL)-5-(THIENYL OR FURYL)-1,2,4-TRIAZOLES | DOW AGROSCIENCES LLC (US) | 2002-01-30 | — | — | EP | disclosed |
| US-6262305-B1 | Process and intermediates for preparing 3-(substituted phenyl)-5-(thienyl or furyl)-1,2,4-triazole compounds | DOW AGROSCIENCES LLC | 2001-07-17 | — | — | US | disclosed |
| US-6015826-A | INSECTICIDES, APHIDICIDES, AND MITICIDES | DOW AGROSCIENCES LLC | 2000-01-18 | — | — | US | disclosed |