Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7526323 | 0.92 | PDE2A (0.34) | NR1H2NR1H3NPC1RAB9ATRPM8 | |
| SCHEMBL7471708 | 0.86 | NR1H2 (0.38) | NR1H2NR1H3NPC1RAB9ATRPM8 | |
| SCHEMBL5726642 | 0.83 | PDE2A (0.33) | NR1H2NR1H3NPC1RAB9ATRPM8 | |
| SCHEMBL5202844 | 0.79 | PDE2A (0.35) | NR1H2NR1H3NPC1RAB9ATRPM8 | |
| SCHEMBL6073454 | 0.78 | PDE2A (0.33) | NR1H2NR1H3NPC1RAB9ATRPM8 | |
| SCHEMBL7477066 | 0.77 | MAPT (0.39) | NR1H2NR1H3NPC1RAB9ATRPM8 | |
| SCHEMBL7532307 | 0.76 | PDE2A (0.33) | NR1H2NR1H3NPC1RAB9ATRPM8 | |
| SCHEMBL5726652 | 0.73 | PKM (0.34) | NR1H2NR1H3NPC1RAB9AHSD17B2 | |
| SCHEMBL6976971 | 0.73 | GAA (0.35) | NR1H2NR1H3 | |
| SCHEMBL5727053 | 0.73 | PDE2A (0.33) | NR1H2NR1H3NPC1RAB9ATRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0922043-B1 | PESTICIDAL 3-(SUBSTITUTED PHENYL)-5-(THIENYL OR FURYL)-1,2,4-TRIAZOLES | DOW AGROSCIENCES LLC (US) | 2002-01-30 | — | — | EP | disclosed |
| US-6262305-B1 | Process and intermediates for preparing 3-(substituted phenyl)-5-(thienyl or furyl)-1,2,4-triazole compounds | DOW AGROSCIENCES LLC | 2001-07-17 | — | — | US | disclosed |
| US-6015826-A | INSECTICIDES, APHIDICIDES, AND MITICIDES | DOW AGROSCIENCES LLC | 2000-01-18 | — | — | US | disclosed |