Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL7480922 | 0.99 | NISCH (0.30) | NISCH | |
| SCHEMBL7480722 | 0.81 | CYP19A1 (0.41) | NISCHSLC6A2 | |
| SCHEMBL7480314 | 0.80 | ALDH1A1 (0.34) | MEN1KMT2A | |
| SCHEMBL27510913 | 0.79 | MEN1 (0.33) | MEN1KMT2ATAAR1SLC6A2 | |
| Bromide SCHEMBL7478970 | 0.79 | CYP19A1 (0.40) | NISCHSLC6A2 | |
| SCHEMBL7480188 | 0.76 | KCNH2 (0.35) | — | |
| Hydrochloric Acid SCHEMBL7481921 | 0.75 | KCNH2 (0.34) | — | |
| SCHEMBL7534680 | 0.74 | NAMPT (0.33) | — | |
| SCHEMBL7481050 | 0.74 | KCNMA1 (0.35) | NISCHMEN1KMT2ASLC6A2 | |
| SCHEMBL7481558 | 0.73 | CYP19A1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0950056-B1 | N-(PYRIDINYLAMINO)ISOINDOLINES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2002-09-18 | — | — | EP | claimed |
| CN-1242012-A | N- (pyridylamino) isoindolines and related compounds | HOECHST MARION ROUSSEL INC (US) | 2000-01-19 | — | — | CN | claimed |
| CN-1242012-A | N- (pyridylamino) isoindolines and related compounds | HOECHST MARION ROUSSEL INC (US) | 2000-01-19 | — | — | CN | disclosed |