Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7484298 | 0.85 | NAMPT (0.36) | NAMPTKDM4ELMNAHSD17B10ALDH1A1 | |
| SCHEMBL7539760 | 0.81 | GAA (0.33) | NAMPTLMNAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL7480188 | 0.76 | KCNH2 (0.35) | KDM4EGAA | |
| Hydrochloric Acid SCHEMBL7481921 | 0.75 | KCNH2 (0.34) | KDM4EALDH1A1GAA | |
| SCHEMBL7477144 | 0.74 | NISCH (0.31) | — | |
| Bromide SCHEMBL7480922 | 0.73 | NISCH (0.30) | — | |
| SCHEMBL7482870 | 0.71 | ABHD6 (0.48) | NAMPTSMN1; SMN2 | |
| SCHEMBL7480314 | 0.71 | ALDH1A1 (0.34) | ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7481798 | 0.70 | ABHD6 (0.46) | NAMPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7481794 | 0.70 | ABHD6 (0.46) | NAMPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0950056-B1 | N-(PYRIDINYLAMINO)ISOINDOLINES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2002-09-18 | — | — | EP | claimed |