Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7484584 | 0.77 | ALDH1A1 (0.44) | ALDH1A1KMT2ASMN1; SMN2MAPTHTT | |
| SCHEMBL7479429 | 0.72 | HPGD (0.49) | HPGDHSD17B10ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL7487235 | 0.70 | HPGD (0.47) | HPGDHSD17B10ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL11389834 | 0.66 | ALDH1A1 (0.49) | HPGDHSD17B10ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL9530474 | 0.65 | MAPK1 (0.53) | HPGDHSD17B10ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL11784164 | 0.64 | FBP1 (0.69) | HPGDHSD17B10ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL7483635 | 0.64 | HSD17B10 (0.47) | HPGDHSD17B10ALDH1A1KMT2AGRIN2B | |
| SCHEMBL8779356 | 0.62 | FBP1 (0.56) | HPGDHSD17B10ALDH1A1SMN1; SMN2FBP1 | |
| SCHEMBL3906094 | 0.62 | MAPK1 (0.62) | HPGDHSD17B10ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL5945366 | 0.61 | IDO1 (0.54) | HSD17B10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999020617-A1 | ANTIINFLAMMATORY THIADIAZOLYL UREAS WHICH ACT AS LFA-1 AND MAC-1 INHIBITORS | ACTIVE BIOTECH AB (SE) | 1999-04-29 | — | — | WO | disclosed |