Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7473955 | 0.87 | MGLL (0.53) | MGLLMEN1KMT2ADGAT1SIGMAR1 | |
| SCHEMBL7390914 | 0.87 | DGAT1 (0.55) | MGLLKMT2ADGAT1ALDH1A1KDM4E | |
| SCHEMBL7389702 | 0.86 | MGLL (0.47) | MGLLDGAT1SIGMAR1ALDH1A1TSHR | |
| SCHEMBL5530617 | 0.85 | SIGMAR1 (0.45) | MGLLDGAT1SIGMAR1ITGB3ITGA2B | |
| SCHEMBL7388878 | 0.84 | MAPT (0.46) | MGLLMEN1KMT2ADGAT1SIGMAR1 | |
| SCHEMBL7384950 | 0.84 | FABP6 (0.46) | MGLLDGAT1SIGMAR1ALDH1A1KDM4E | |
| SCHEMBL7384777 | 0.82 | MEN1 (0.46) | MEN1KMT2ASIGMAR1ALDH1A1KDM4E | |
| SCHEMBL27541033 | 0.82 | MEN1 (0.43) | MGLLMEN1KMT2ADGAT1ALDH1A1 | |
| SCHEMBL7393385 | 0.82 | SIGMAR1 (0.48) | DGAT1SIGMAR1ALDH1A1TSHRLMNA | |
| SCHEMBL7386854 | 0.81 | DGAT1 (0.42) | DGAT1SIGMAR1TP53LMNAITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1056743-A1 | BENZAMINE DERIVATIVES | MERCK PATENT GmbH (DE) | 2000-12-06 | — | — | EP | disclosed |
| WO-1999031092-A1 | BENZAMINE DERIVATIVES | MERCK PATENT GMBH (DE) | 1999-06-24 | — | — | WO | disclosed |