Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 8/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.45 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7389702 | 0.91 | MGLL (0.47) | MGLLSIGMAR1DGAT1ITGB3ITGA2B | |
| SCHEMBL5530617 | 0.89 | SIGMAR1 (0.45) | MGLLSIGMAR1DGAT1ITGB3ITGA2B | |
| SCHEMBL7384950 | 0.88 | FABP6 (0.46) | MGLLSIGMAR1DGAT1ITGB3ITGA2B | |
| SCHEMBL7387996 | 0.87 | SIGMAR1 (0.49) | MGLLSIGMAR1HDAC4ITGB3ITGA2B | |
| SCHEMBL7477320 | 0.87 | MGLL (0.47) | MGLLSIGMAR1DGAT1ITGB3ITGA2B | |
| SCHEMBL7393385 | 0.87 | SIGMAR1 (0.48) | SIGMAR1DGAT1 | |
| SCHEMBL7388176 | 0.86 | SIGMAR1 (0.51) | MGLLSIGMAR1KMT2AMEN1 | |
| SCHEMBL7387185 | 0.85 | TSHR (0.50) | SIGMAR1 | |
| SCHEMBL7388548 | 0.85 | MAPT (0.45) | SIGMAR1POLB | |
| SCHEMBL7386854 | 0.84 | DGAT1 (0.42) | SIGMAR1DGAT1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1056743-A1 | BENZAMINE DERIVATIVES | MERCK PATENT GmbH (DE) | 2000-12-06 | — | — | EP | disclosed |
| WO-1999031092-A1 | BENZAMINE DERIVATIVES | MERCK PATENT GMBH (DE) | 1999-06-24 | — | — | WO | disclosed |