Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 13/20 | 0.35 |
| ▸ | PPARA | Q07869 | 13/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 10/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7471419 | 0.79 | NFE2L2 (0.45) | MAPTPPARDPPARAALDH1A1LMNA | |
| SCHEMBL22349810 | 0.77 | MAPT (0.64) | MAPTPPARDPPARAALDH1A1LMNA | |
| SCHEMBL20644484 | 0.75 | ALDH1A1 (0.48) | MAPTPPARDPPARAKDM4EALDH1A1 | |
| SCHEMBL14280089 | 0.75 | MAPT (0.51) | MAPTHSD17B3PPARDPPARAALDH1A1 | |
| SCHEMBL20639751 | 0.73 | MAPT (0.46) | MAPTPPARDPPARAKDM4EALDH1A1 | |
| SCHEMBL31729279 | 0.72 | CHRNB2 (0.38) | MAPTHSD17B3ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL11070043 | 0.70 | MAPT (0.62) | MAPTKDM4EALDH1A1LMNAGAA | |
| SCHEMBL31704514 | 0.70 | HSD17B3 (0.34) | MAPTHSD17B3 | |
| SCHEMBL13114811 | 0.70 | ADRB1 (0.49) | MAPTKDM4EALDH1A1LMNAGAA | |
| SCHEMBL25277634 | 0.69 | TP53 (0.40) | MAPTALDH1A1LMNASMN1; SMN2ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0844825-B1 | INSECTICIDAL N-(SUBSTITUTED ARYLMETHYL)-4- BIS(SUBSTITUTED PHENYL OR PYRIDYL)METHYL]PIPERIDINES | FMC CORP (US) | 2002-11-27 | — | — | EP | disclosed |
| US-6214845-B1 | AGRICULTURE | FMC CORPORATION | 2001-04-10 | — | — | US | disclosed |
| US-6184234-B1 | EFFECTIVE AGRICULTURAL PESTICIDE FOR TOBACCO, BEETS, BEANS, CABBAGE CROPS | FMC CORPORATION | 2001-02-06 | — | — | US | disclosed |
| EP-0844825-A4 | INSECTICIDAL N-(SUBSTITUTED ARYLMETHYL)-4- BIS(SUBSTITUTED PHENYL OR PYRIDYL)METHYL]PIPERIDINES | FMC CORP (US) | 2000-04-05 | — | — | EP | disclosed |
| US-6030987-A | Insecticidal N-(substituted arylmethyl)-4-[bis(substituted phenyl or pyridyl)methyl]piperidines | FMC CORPORATION (US) | 2000-02-29 | — | — | US | disclosed |
| EP-0844825-A1 | INSECTICIDAL N-(SUBSTITUTED ARYLMETHYL)-4- BIS(SUBSTITUTED PHENYL OR PYRIDYL)METHYL]PIPERIDINES | FMC CORPORATION (US) | 1998-06-03 | — | — | EP | disclosed |
| US-5639763-A | FOR AGRICULTURAL APPLICATIONS | FMC CORPORATION (US) | 1997-06-17 | — | — | US | disclosed |
| WO-1996036228-A1 | INSECTICIDAL N-(SUBSTITUTED ARYLMETHYL)-4-[BIS(SUBSTITUTED PHENYL OR PYRIDYL)METHYL]PIPERIDINES | FMC CORPORATION (US) | 1996-11-21 | — | — | WO | disclosed |
| US-5569664-A | AGRICULTURAL INSECTICIDES | FMC CORPORATION (US) | 1996-10-29 | — | — | US | disclosed |