Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TLR4 | O00206 | 1/20 | 0.37 |
| ▸ | OGA | O60502 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27654826 | 0.74 | ATM (0.48) | ATMALDH1A1KDM4ETLR4OGA | |
| SCHEMBL8086087 | 0.74 | POLB (0.47) | ATMMTNR1AMTNR1B | |
| SCHEMBL7464313 | 0.72 | LMNA (0.43) | EPHX1MEN1KMT2A | |
| SCHEMBL7619156 | 0.72 | LMNA (0.43) | EPHX1MEN1KMT2A | |
| SCHEMBL27077256 | 0.71 | EPHX1 (0.34) | ATMEPHX1MEN1KMT2A | |
| SCHEMBL6026414 | 0.71 | SIGMAR1 (0.36) | ALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7454269 | 0.71 | LMNA (0.43) | EPHX1MEN1KMT2A | |
| SCHEMBL7476219 | 0.71 | CHRM2 (0.31) | — | |
| SCHEMBL7474652 | 0.70 | CHRNB2 (0.33) | — | |
| SCHEMBL6906842 | 0.69 | TSHR (0.42) | ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933361-B1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO CO LTD (JP) | 2002-03-27 | — | — | EP | disclosed |
| US-6057337-A | USEFUL FOR CARE, IMPROVEMENT OR PREVENTION OF HAIR LOSS | SHISEIDO CO., LTD. (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0933361-A1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO COMPANY LIMITED (JP) | 1999-08-04 | — | — | EP | disclosed |