Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 2/20 | 0.33 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7482383 | 0.91 | PLG (0.33) | HDAC6HDAC1PLGACSS2 | |
| SCHEMBL7478886 | 0.89 | PLG (0.33) | HDAC6HDAC1PLGACSS2 | |
| SCHEMBL7484578 | 0.88 | PLG (0.33) | HDAC6HDAC1PLGACSS2 | |
| SCHEMBL7122845 | 0.80 | GRN (0.37) | PLG | |
| SCHEMBL7489855 | 0.78 | PIN1 (0.46) | MAPK1ALDH1A1ACSS2 | |
| Hydrochloric Acid SCHEMBL7478353 | 0.77 | PIN1 (0.45) | MAPK1ALDH1A1ACSS2 | |
| SCHEMBL7073159 | 0.76 | TP53 (0.36) | PDE2APLGACSS2 | |
| SCHEMBL7067767 | 0.75 | NR1H4 (0.42) | HDAC6HDAC1HDAC10 | |
| SCHEMBL7478946 | 0.74 | ACSS2 (0.39) | HDAC6HDAC1ALDH1A1ACSS2 | |
| SCHEMBL7485438 | 0.74 | PIN1 (0.37) | HDAC6HDAC1PLGACSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000020400-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR TREATING HEPATITIS C INFECTIONS | AXYS PHARMACEUTICALS, INC. (US) | 2000-04-13 | — | — | WO | disclosed |