Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 10/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.32 |
| ▸ | ACSS2 | Q9NR19 | 2/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7484578 | 0.93 | PLG (0.33) | PLGNR1H4ACSS2PIN1HDAC6 | |
| SCHEMBL7482383 | 0.93 | PLG (0.33) | PLGNR1H4ACSS2PIN1HDAC6 | |
| SCHEMBL7477974 | 0.91 | PLG (0.32) | PLGNR1H4ACSS2 | |
| SCHEMBL7477644 | 0.89 | MAPK1 (0.38) | PLGACSS2HDAC6HDAC1 | |
| SCHEMBL7122845 | 0.85 | GRN (0.37) | PLGNR1H4 | |
| SCHEMBL7073159 | 0.80 | TP53 (0.36) | PLGACSS2 | |
| SCHEMBL7074567 | 0.80 | TAS1R3 (0.38) | PLGNR1H4 | |
| SCHEMBL7489855 | 0.79 | PIN1 (0.46) | ACSS2PIN1 | |
| Hydrochloric Acid SCHEMBL7478353 | 0.79 | PIN1 (0.45) | ACSS2PIN1 | |
| SCHEMBL7482199 | 0.78 | PIN1 (0.38) | PLGACSS2PIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000020400-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR TREATING HEPATITIS C INFECTIONS | AXYS PHARMACEUTICALS, INC. (US) | 2000-04-13 | — | — | WO | disclosed |