Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.42 |
| ▸ | SLC6A7 | Q99884 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7478027 | 0.77 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2AUSP2TSHR | |
| SCHEMBL7477635 | 0.75 | PPARG (0.52) | TSHRSERPINE1PPARG | |
| SCHEMBL7477006 | 0.74 | SERPINE1 (0.51) | SERPINE1PPARG | |
| SCHEMBL7524721 | 0.70 | KMT2A (0.57) | ALDH1A1MEN1KMT2ALMNAKDM4E | |
| SCHEMBL7475482 | 0.70 | POLB (0.44) | ALDH1A1MEN1KMT2ATSHRKDM4E | |
| SCHEMBL10724385 | 0.70 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2AUSP2TSHR | |
| SCHEMBL14233800 | 0.69 | PPARG (0.70) | PPARG | |
| SCHEMBL27583578 | 0.69 | SERPINE1 (0.41) | SERPINE1PPARGPOLB | |
| SCHEMBL31729754 | 0.68 | FLT1 (0.50) | ALDH1A1USP2LMNASERPINE1POLB | |
| SCHEMBL7479293 | 0.68 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2AUSP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1210343-A2 | BENZOIC ACID DERIVATIVES AND THEIR USE AS PPAR RECEPTOR AGONISTS | AstraZeneca AB (SE) | 2002-06-05 | — | — | EP | disclosed |
| WO-2001012187-A2 | BENZOIC ACID DERIVATIVES AND THEIR USE AS PPAR RECEPTOR AGONISTS | ASTRAZENECA AB (SE) | 2001-02-22 | — | — | WO | disclosed |