Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SLC6A7 | Q99884 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TACR3 | P29371 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7478024 | 0.77 | ALDH1A1 (0.52) | ALDH1A1TSHRMEN1KMT2AUSP2 | |
| SCHEMBL7477639 | 0.74 | TSHR (0.51) | ALDH1A1TSHRKMT2APOLBKDM4E | |
| SCHEMBL7483897 | 0.73 | F2 (0.45) | ALDH1A1TSHRLMNAKDM4EHSD17B10 | |
| SCHEMBL7475485 | 0.69 | MMP12 (0.42) | ALDH1A1TSHRMEN1KMT2AKDM4E | |
| SCHEMBL10724385 | 0.67 | ALDH1A1 (1.00) | ALDH1A1TSHRMEN1KMT2AUSP2 | |
| SCHEMBL7474579 | 0.65 | ALDH1A1 (0.54) | ALDH1A1TSHRMEN1KMT2AUSP2 | |
| SCHEMBL7482853 | 0.64 | HRH3 (0.50) | ALDH1A1TSHRMEN1KMT2ALMNA | |
| SCHEMBL2735943 | 0.64 | HRH4 (0.70) | ALDH1A1TSHRMEN1KMT2ALMNA | |
| SCHEMBL27300769 | 0.64 | HRH4 (0.71) | ALDH1A1TSHRMEN1KMT2AUSP2 | |
| SCHEMBL7474003 | 0.63 | HRH3 (0.60) | ALDH1A1TSHRMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1210343-A2 | BENZOIC ACID DERIVATIVES AND THEIR USE AS PPAR RECEPTOR AGONISTS | AstraZeneca AB (SE) | 2002-06-05 | — | — | EP | disclosed |
| WO-2001012187-A2 | BENZOIC ACID DERIVATIVES AND THEIR USE AS PPAR RECEPTOR AGONISTS | ASTRAZENECA AB (SE) | 2001-02-22 | — | — | WO | disclosed |