Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 4/20 | 0.51 |
| ▸ | PPARG | P37231 | 8/20 | 0.47 |
| ▸ | METTL3 | Q86U44 | 3/20 | 0.44 |
| ▸ | METTL14 | Q9HCE5 | 3/20 | 0.44 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7477635 | 0.89 | PPARG (0.52) | SERPINE1PPARGNTSR1 | |
| SCHEMBL7524721 | 0.79 | KMT2A (0.57) | HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL7475482 | 0.79 | POLB (0.44) | SERPINE1PPARGHDAC2 | |
| SCHEMBL4943532 | 0.78 | HTR6 (0.52) | SERPINE1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL27583578 | 0.78 | SERPINE1 (0.41) | SERPINE1PPARGNTSR1 | |
| SCHEMBL7482851 | 0.77 | PPARG (0.51) | SERPINE1PPARGNTSR1 | |
| SCHEMBL7478024 | 0.74 | ALDH1A1 (0.52) | SERPINE1PPARG | |
| SCHEMBL14233800 | 0.73 | PPARG (0.70) | PPARG | |
| SCHEMBL7014848 | 0.72 | HDAC8 (0.68) | PPARGHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL30185513 | 0.72 | HDAC8 (0.68) | PPARGHDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1379774-A | Compounds | ASTRAZENECA AB (SE) | 2002-11-13 | — | — | CN | disclosed |
| EP-1210343-A2 | BENZOIC ACID DERIVATIVES AND THEIR USE AS PPAR RECEPTOR AGONISTS | AstraZeneca AB (SE) | 2002-06-05 | — | — | EP | disclosed |
| WO-2001012187-A2 | BENZOIC ACID DERIVATIVES AND THEIR USE AS PPAR RECEPTOR AGONISTS | ASTRAZENECA AB (SE) | 2001-02-22 | — | — | WO | disclosed |