Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 19/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.47 |
| ▸ | ITGAV | P06756 | 13/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7468971 | 0.85 | ITGB3 (0.42) | ITGB3ITGA2BITGAV | |
| SCHEMBL7474864 | 0.84 | TMEM97 (0.39) | — | |
| Trifluoroacetic Acid SCHEMBL7476025 | 0.83 | ITGB3 (0.53) | ITGB3ITGA2BITGAV | |
| SCHEMBL7473247 | 0.80 | NR1H2 (0.47) | — | |
| SCHEMBL7481405 | 0.79 | NR1H2 (0.42) | ITGB3ITGA2B | |
| SCHEMBL7468291 | 0.78 | NR1H2 (0.38) | — | |
| SCHEMBL7419930 | 0.75 | NR1H2 (0.49) | — | |
| Trifluoroacetic Acid SCHEMBL7480684 | 0.74 | ITGB3 (0.49) | ITGB3ITGA2BITGAV | |
| SCHEMBL7468540 | 0.74 | ITGB3 (0.39) | ITGB3ITGA2BITGAV | |
| SCHEMBL7469768 | 0.74 | MAPT (0.41) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0777667-A1 | CYCLIC BENZAZEPINE UREA DERIVATIVES WITH AGGREGATION-INHIBITING EFFECT | Dr. Karl Thomae GmbH (DE) | 1997-06-11 | — | — | EP | disclosed |
| WO-1996005194-A1 | CYCLIC BENZAZEPINE UREA DERIVATIVES WITH AGGREGATION-INHIBITING EFFECT | DR. KARL THOMAE GMBH (DE) | 1996-02-22 | — | — | WO | disclosed |