Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 6/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | SSTR4 | P31391 | 3/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
| ▸ | CASR | P41180 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.30 |
| ▸ | SSTR2 | P30874 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7428754 | 0.77 | GBA1 (0.39) | GBA1SSTR4POLBSSTR2 | |
| SCHEMBL10374977 | 0.77 | GBA1 (0.36) | GBA1 | |
| SCHEMBL9867117 | 0.77 | L3MBTL1 (0.43) | NPC1RAB9AKDM4EPOLB | |
| SCHEMBL9866251 | 0.75 | SIGMAR1 (0.42) | NPC1RAB9ATSHR | |
| SCHEMBL7428749 | 0.75 | GBA1 (0.36) | GBA1 | |
| Hydrochloric Acid SCHEMBL9827936 | 0.74 | GBA1 (0.35) | GBA1 | |
| SCHEMBL7425273 | 0.71 | SSTR4 (0.47) | GBA1AGTR1SSTR4ALDH1A1SSTR2 | |
| SCHEMBL9865107 | 0.70 | SMN1; SMN2 (0.40) | RAB9ASMN1; SMN2MTNR1AMTNR1B | |
| SCHEMBL8617900 | 0.70 | RAB9A (0.43) | NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9867346 | 0.70 | HRH3 (0.45) | NPC1RAB9ASMN1; SMN2MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019050-B1 | USE OF SOMATOSTATIN AGONISTS AND ANTAGONISTS FOR TREATING DISEASES RELATED TO THE EYE | NOVO NORDISK AS (DK) | 2002-03-20 | — | — | EP | claimed |