Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.47 |
| ▸ | ITGAV | P06756 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | GLS | O94925 | 8/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7477666 | 0.80 | GLS (0.52) | ITGB3ITGAVALDH1A1GLSNPC1 | |
| SCHEMBL7475334 | 0.78 | GLS (0.53) | ITGB3ITGAVGLSNPC1KMT2A | |
| SCHEMBL7482916 | 0.78 | KMT2A (0.51) | ITGB3ITGAVALDH1A1NPC1KMT2A | |
| SCHEMBL7481216 | 0.77 | NPC1 (0.54) | ITGB3ITGAVALDH1A1NPC1KMT2A | |
| SCHEMBL7480443 | 0.76 | NPC1 (0.52) | ALDH1A1NPC1KMT2ASMN1; SMN2POLB | |
| SCHEMBL7477721 | 0.76 | NPC1 (0.52) | ALDH1A1NPC1KMT2ASMN1; SMN2POLB | |
| SCHEMBL7476548 | 0.75 | MAPT (0.54) | ITGB3ITGAVNPC1KMT2ASMN1; SMN2 | |
| SCHEMBL7480839 | 0.74 | GLS (0.55) | ALDH1A1PKMGLSNPC1SMN1; SMN2 | |
| SCHEMBL7486396 | 0.71 | SMN1; SMN2 (0.41) | ITGB3ITGAVALDH1A1NPC1KMT2A | |
| SCHEMBL21325661 | 0.71 | GLS (0.70) | PKMGLSSMN1; SMN2POLBCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999020618-A1 | THIADIAZOLES AMIDES USEFUL AS ANTIINFLAMMATORY AGENTS | ACTIVE BIOTECH AB (SE) | 1999-04-29 | — | — | WO | claimed |