Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 8/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 3/20 | 0.47 |
| ▸ | SRC | P12931 | 3/20 | 0.47 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.46 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7482445 | 0.83 | MAPT (0.63) | RAB9ASMN1; SMN2NPC1TP53MAPT | |
| SCHEMBL7474057 | 0.76 | MAPT (0.61) | RAB9ASMN1; SMN2NPC1TP53MAPT | |
| SCHEMBL7477984 | 0.76 | MAPT (0.56) | RAB9ASMN1; SMN2NPC1TP53MAPT | |
| SCHEMBL7478620 | 0.74 | ITGB3 (0.47) | GLSRAB9ASMN1; SMN2PKMNPC1 | |
| SCHEMBL7476548 | 0.74 | MAPT (0.54) | RAB9ASMN1; SMN2NPC1TP53MAPT | |
| SCHEMBL7482437 | 0.74 | MAPT (0.53) | RAB9ASMN1; SMN2NPC1TP53MAPT | |
| SCHEMBL7478572 | 0.73 | MAPT (0.57) | RAB9ASMN1; SMN2NPC1TP53MAPT | |
| SCHEMBL7476148 | 0.72 | MAPT (0.61) | RAB9ASMN1; SMN2NPC1TP53MAPT | |
| SCHEMBL7479785 | 0.72 | POLB (0.48) | GLSRAB9ASMN1; SMN2NPC1TP53 | |
| SCHEMBL25387786 | 0.72 | ALDH1A1 (0.74) | GLSRAB9ASMN1; SMN2PKMNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999020618-A1 | THIADIAZOLES AMIDES USEFUL AS ANTIINFLAMMATORY AGENTS | ACTIVE BIOTECH AB (SE) | 1999-04-29 | — | — | WO | claimed |
| WO-1999020618-A1 | THIADIAZOLES AMIDES USEFUL AS ANTIINFLAMMATORY AGENTS | ACTIVE BIOTECH AB (SE) | 1999-04-29 | — | — | WO | disclosed |