Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | GLB1 | P16278 | 1/20 | 0.47 |
| ▸ | CTRC | Q99895 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | G6PD | P11413 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7481216 | 0.85 | NPC1 (0.54) | NPC1SMN1; SMN2KMT2APOLBRAB9A | |
| SCHEMBL7477721 | 0.84 | NPC1 (0.52) | NPC1SMN1; SMN2KMT2APOLBRAB9A | |
| SCHEMBL7482916 | 0.80 | KMT2A (0.51) | NPC1SMN1; SMN2KMT2APOLBRAB9A | |
| SCHEMBL7477666 | 0.78 | GLS (0.52) | NPC1SMN1; SMN2KMT2APOLBRAB9A | |
| SCHEMBL7475334 | 0.77 | GLS (0.53) | NPC1SMN1; SMN2KMT2APOLBMAPT | |
| SCHEMBL7478620 | 0.76 | ITGB3 (0.47) | NPC1SMN1; SMN2KMT2APOLBRAB9A | |
| SCHEMBL7476548 | 0.76 | MAPT (0.54) | NPC1SMN1; SMN2KMT2ARAB9ABLM | |
| SCHEMBL7474910 | 0.73 | CBLB (0.50) | NPC1SMN1; SMN2KMT2AGLB1CTRC | |
| SCHEMBL7481105 | 0.73 | RAB9A (0.51) | NPC1SMN1; SMN2KMT2APOLBRAB9A | |
| SCHEMBL7486396 | 0.70 | SMN1; SMN2 (0.41) | NPC1SMN1; SMN2KMT2ARAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999020618-A1 | THIADIAZOLES AMIDES USEFUL AS ANTIINFLAMMATORY AGENTS | ACTIVE BIOTECH AB (SE) | 1999-04-29 | — | — | WO | disclosed |