Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 6/20 | 0.39 |
| ▸ | TPSD1 | Q9BZJ3 | 6/20 | 0.39 |
| ▸ | TPSG1 | Q9NRR2 | 6/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 4/20 | 0.37 |
| ▸ | ACSS2 | Q9NR19 | 4/20 | 0.37 |
| ▸ | TYMS | P04818 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | FPGS | Q05932 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7485136 | 0.84 | TPSAB1 (0.39) | TPSAB1TPSD1TPSG1PIN1ACSS2 | |
| SCHEMBL2526178 | 0.82 | PIN1 (0.41) | PIN1ACSS2PIK3CDPIK3CB | |
| SCHEMBL2526173 | 0.82 | PIN1 (0.41) | PIN1ACSS2PIK3CDPIK3CB | |
| SCHEMBL2528847 | 0.80 | PIN1 (0.39) | TPSAB1TPSD1TPSG1PIN1ACSS2 | |
| SCHEMBL2528844 | 0.80 | PIN1 (0.39) | TPSAB1TPSD1TPSG1PIN1ACSS2 | |
| SCHEMBL7481691 | 0.79 | PIN1 (0.41) | TPSAB1TPSD1TPSG1PIN1ACSS2 | |
| Hydrochloric Acid SCHEMBL7477525 | 0.79 | PIN1 (0.40) | TPSAB1TPSD1TPSG1PIN1ACSS2 | |
| SCHEMBL7485438 | 0.76 | PIN1 (0.37) | TPSAB1TPSD1TPSG1PIN1ACSS2 | |
| SCHEMBL7479311 | 0.75 | ACSS2 (0.37) | TPSAB1TPSD1TPSG1PIN1ACSS2 | |
| SCHEMBL7486158 | 0.72 | ACSS2 (0.38) | TPSAB1TPSD1TPSG1PIN1ACSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000020400-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR TREATING HEPATITIS C INFECTIONS | AXYS PHARMACEUTICALS, INC. (US) | 2000-04-13 | — | — | WO | disclosed |