Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 6/20 | 0.39 |
| ▸ | TPSD1 | Q9BZJ3 | 6/20 | 0.39 |
| ▸ | TPSG1 | Q9NRR2 | 6/20 | 0.39 |
| ▸ | ACSS2 | Q9NR19 | 6/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.35 |
| ▸ | PLG | P00747 | 2/20 | 0.35 |
| ▸ | TYMS | P04818 | 1/20 | 0.34 |
| ▸ | FPGS | Q05932 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7485438 | 0.93 | PIN1 (0.37) | TPSAB1TPSD1TPSG1ACSS2PIN1 | |
| SCHEMBL7479311 | 0.90 | ACSS2 (0.37) | TPSAB1TPSD1TPSG1ACSS2PIN1 | |
| SCHEMBL7486158 | 0.87 | ACSS2 (0.38) | TPSAB1TPSD1TPSG1ACSS2PIN1 | |
| SCHEMBL7482199 | 0.85 | PIN1 (0.38) | TPSAB1TPSD1TPSG1ACSS2PIN1 | |
| SCHEMBL7478923 | 0.84 | TPSAB1 (0.39) | TPSAB1TPSD1TPSG1ACSS2PIN1 | |
| SCHEMBL7490565 | 0.83 | PIN1 (0.41) | TPSAB1TPSD1TPSG1ACSS2PIN1 | |
| SCHEMBL7489855 | 0.82 | PIN1 (0.46) | ACSS2PIN1 | |
| Hydrochloric Acid SCHEMBL7478353 | 0.81 | PIN1 (0.45) | ACSS2PIN1 | |
| SCHEMBL7478946 | 0.80 | ACSS2 (0.39) | ACSS2PIN1 | |
| SCHEMBL7421962 | 0.80 | PIN1 (0.35) | ACSS2PIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000020400-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR TREATING HEPATITIS C INFECTIONS | AXYS PHARMACEUTICALS, INC. (US) | 2000-04-13 | — | — | WO | disclosed |