Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.35 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8064164 | 0.79 | ALDH1A1 (0.44) | APPALDH1A1TSHRCYP3A4MAPK1 | |
| SCHEMBL5925342 | 0.78 | APP (0.46) | APPALDH1A1TSHRALOX15HSD17B10 | |
| SCHEMBL5496841 | 0.78 | TSHR (0.43) | TSHRNOTUMFYN | |
| SCHEMBL16720012 | 0.75 | PRKCI (0.51) | CYP3A4MAPTFYN | |
| SCHEMBL9739215 | 0.75 | APP (0.41) | APPALDH1A1TSHRCYP3A4MAPK1 | |
| SCHEMBL7479982 | 0.74 | ALDH1A1 (0.40) | ALDH1A1TSHRCYP3A4MAPK1TDP1 | |
| SCHEMBL8063028 | 0.72 | APP (0.49) | APPALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL8563667 | 0.72 | FYN (0.45) | ALDH1A1MAPK1HSD17B10SMN1; SMN2FYN | |
| SCHEMBL7326388 | 0.71 | AOC3 (0.58) | APPAOC3FYNHDAC6 | |
| SCHEMBL3240177 | 0.71 | NOS1 (0.41) | ALDH1A1CYP3A4TDP1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0363223-A2 | 3-Aryloxymethyl-cephalosporin derivatives, their preparation and their medical use | Sankyo Company Limited (JP) | 1990-04-11 | — | — | EP | disclosed |