Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 18/20 | 0.42 |
| ▸ | ITGB7 | P26010 | 18/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 7/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3593039 | 0.82 | ALDH1A1 (0.46) | ITGA4ITGB7ITGB1 | |
| Hydrochloric Acid SCHEMBL3593038 | 0.81 | ALDH1A1 (0.47) | ITGA4ITGB7ITGB1 | |
| SCHEMBL7535841 | 0.77 | ITGA4 (0.47) | ITGA4ITGB7ITGB1 | |
| SCHEMBL3531697 | 0.76 | ITGA4 (0.62) | ITGA4ITGB7ITGB1 | |
| SCHEMBL11924843 | 0.74 | MIF (0.46) | MIF | |
| SCHEMBL27323338 | 0.74 | MIF (0.62) | MIF | |
| SCHEMBL15729872 | 0.74 | LDHA (0.53) | MIF | |
| SCHEMBL820965 | 0.72 | MIF (0.56) | MIFLMNACYP2C9 | |
| SCHEMBL5399978 | 0.72 | MIF (0.56) | MIFLMNACYP2C9 | |
| SCHEMBL135996 | 0.72 | MIF (0.56) | MIFLMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002008202-A2 | ALPHA AMINO ACID DERIVATIVES--INHIBITORS OF LEUKOCYTE ADHESION MEDIATED BY VLA-4 | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-31 | — | — | WO | disclosed |