Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 7/20 | 0.59 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.59 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.59 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.59 |
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1271627 | 0.94 | OPRL1 (0.70) | OPRL1OPRM1OPRD1OPRK1DRD2 | |
| SCHEMBL9395829 | 0.89 | OPRM1 (0.64) | OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL9395676 | 0.83 | OPRL1 (0.71) | OPRL1OPRM1OPRD1OPRK1DRD2 | |
| SCHEMBL1271664 | 0.83 | OPRM1 (0.74) | OPRL1OPRM1OPRD1OPRK1DRD2 | |
| SCHEMBL4444487 | 0.80 | CHRM1 (0.72) | OPRM1OPRK1DRD2HTR1AADRA2A | |
| SCHEMBL9395659 | 0.80 | OPRL1 (0.55) | OPRL1OPRM1OPRD1OPRK1SIRT2 | |
| SCHEMBL8612934 | 0.80 | ALDH1A1 (0.59) | OPRL1OPRM1OPRD1OPRK1SIRT2 | |
| SCHEMBL30910142 | 0.80 | OPRL1 (0.86) | OPRL1OPRM1OPRD1OPRK1CHRM1 | |
| SCHEMBL26092381 | 0.80 | OPRL1 (0.86) | OPRL1OPRM1OPRD1OPRK1CHRM1 | |
| SCHEMBL9395620 | 0.79 | SIRT2 (0.77) | OPRL1OPRM1OPRD1OPRK1SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799224-B1 | QUINOXALINES AND DRUGS PREPARED THEREFROM | BASF AG (DE) | 2002-04-17 | — | — | EP | disclosed |
| US-5852017-A | 2,3(1H,4H)-quinoxalinediones | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-22 | — | — | US | disclosed |
| US-5849743-A | Quinoxalines and drugs prepared therefrom | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-15 | — | — | US | disclosed |
| EP-0572852-B1 | Quinoxalin-2,3(1H,4H)-diones used as medicine | BASF AG (DE) | 1998-10-21 | — | — | EP | disclosed |
| US-5714489-A | 2,3(1H,4H)quinoxalinedione | BASF AKTIENGESELLSCHAFT (DE) | 1998-02-03 | — | — | US | disclosed |
| EP-0572852-A1 | Quinoxalin-2,3(1H,4H)-diones used as medicine | BASF Aktiengesellschaft (DE) | 1993-12-08 | — | — | EP | disclosed |