Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 2/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.41 |
| ▸ | MGLL | Q99685 | 2/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7479360 | 0.86 | CHRNB2 (0.46) | ALOX5APFEN1GPR119CHRNA3 | |
| SCHEMBL7407720 | 0.84 | CHRNB2 (0.53) | ALOX5APFEN1GPR119CHRNA3 | |
| SCHEMBL18291358 | 0.84 | ALOX5AP (0.50) | ALOX5APFEN1GPR119CHRNA3 | |
| SCHEMBL7472930 | 0.84 | CHRNB2 (0.54) | ALOX5APFEN1GPR119CHRNA3 | |
| SCHEMBL6588716 | 0.84 | CHRNA3 (0.59) | ALOX5APFEN1GPR119CHRNA3 | |
| SCHEMBL7472876 | 0.84 | CHRNA3 (0.59) | ALOX5APFEN1GPR119CHRNA3 | |
| SCHEMBL7455050 | 0.83 | GPR119 (0.42) | ALOX5APFEN1GPR119CHRNA3 | |
| SCHEMBL7408557 | 0.83 | GPR119 (0.48) | ALOX5APFEN1GPR119CHRNA3 | |
| SCHEMBL6585750 | 0.81 | GPR119 (0.41) | ALOX5APFEN1GPR119CHRNA3 | |
| SCHEMBL7418829 | 0.80 | ALOX5AP (0.53) | ALOX5APFEN1GPR119CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0950057-B1 | 3-PYRIDYL ENANTIOMERS AND THEIR USE AS ANALGESICS | ABBOTT LAB (US) | 2002-11-13 | — | — | EP | disclosed |
| US-6403575-B1 | ANTI-INFLAMMATORIES | ABBOTT LABORATORIES | 2002-06-11 | — | — | US | disclosed |
| US-6133253-A | NEURONAL CELL DEATH PREVENTORS AND ANTI-INFLAMMATORIES | ABBOTT LABORATORIES (US) | 2000-10-17 | — | — | US | disclosed |