Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QDPR | P09417 | 2/20 | 0.66 |
| ▸ | DRD2 | P14416 | 9/20 | 0.58 |
| ▸ | DRD3 | P35462 | 8/20 | 0.54 |
| ▸ | DRD4 | P21917 | 8/20 | 0.51 |
| ▸ | HTR1A | P08908 | 7/20 | 0.51 |
| ▸ | DRD1 | P21728 | 7/20 | 0.51 |
| ▸ | DRD5 | P21918 | 7/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1558037 | 0.86 | DRD2 (0.58) | QDPRDRD2DRD3DRD4HTR1A | |
| SCHEMBL19711151 | 0.84 | QDPR (0.61) | QDPRDRD2DRD3DRD4DRD1 | |
| SCHEMBL27304673 | 0.84 | QDPR (0.69) | QDPRDRD2 | |
| SCHEMBL1091809 | 0.83 | QDPR (0.60) | QDPRDRD2DRD3DRD4DRD1 | |
| SCHEMBL19658654 | 0.83 | QDPR (0.60) | QDPRDRD4 | |
| SCHEMBL2651932 | 0.83 | QDPR (0.60) | QDPR | |
| SCHEMBL1473424 | 0.82 | QDPR (0.61) | QDPR | |
| SCHEMBL14590572 | 0.81 | QDPR (0.61) | QDPRDRD2 | |
| SCHEMBL5670914 | 0.81 | QDPR (0.57) | QDPR | |
| SCHEMBL1558412 | 0.80 | NAMPT (0.54) | DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747357-B1 | Dihydropyridine NPY antagonists: piperidine derivatives | BRISTOL MYERS SQUIBB CO (US) | 2002-01-09 | — | — | EP | disclosed |
| US-5668151-A | USEFUL AS ANOREXIGENIC AGENTS IN PROMOTING WEIGHT LOSS AND TREATING EATING DISORDERS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-09-16 | — | — | US | disclosed |
| EP-0747357-A2 | Dihydropyridine NPY antagonists: piperidine derivatives | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-12-11 | — | — | EP | disclosed |