Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 4/20 | 0.35 |
| ▸ | ACSS2 | Q9NR19 | 2/20 | 0.34 |
| ▸ | PLG | P00747 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | BMPR2 | Q13873 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7489855 | 0.90 | PIN1 (0.46) | IKBKBPIN1ACSS2L3MBTL1KDM4E | |
| Hydrochloric Acid SCHEMBL7478353 | 0.89 | PIN1 (0.45) | IKBKBPIN1ACSS2L3MBTL1KDM4E | |
| SCHEMBL7478946 | 0.88 | ACSS2 (0.39) | IKBKBPIN1ACSS2L3MBTL1NR1H4 | |
| SCHEMBL7421962 | 0.88 | PIN1 (0.35) | IKBKBPIN1ACSS2L3MBTL1NR1H4 | |
| SCHEMBL7482513 | 0.87 | PIN1 (0.41) | PIN1ACSS2L3MBTL1NR1H4 | |
| SCHEMBL7481103 | 0.87 | PIN1 (0.35) | PIN1ACSS2PLGL3MBTL1NR1H4 | |
| SCHEMBL7490565 | 0.87 | PIN1 (0.41) | PIN1ACSS2PLGSMN1; SMN2 | |
| SCHEMBL7482199 | 0.86 | PIN1 (0.38) | IKBKBPIN1ACSS2PLG | |
| SCHEMBL7489355 | 0.86 | PIN1 (0.34) | IKBKBPIN1ACSS2L3MBTL1NR1H4 | |
| SCHEMBL7479311 | 0.82 | ACSS2 (0.37) | PIN1ACSS2PLGHDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000020400-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR TREATING HEPATITIS C INFECTIONS | AXYS PHARMACEUTICALS, INC. (US) | 2000-04-13 | — | — | WO | disclosed |