Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.60 |
| ▸ | CYSLTR1 | Q9Y271 | 7/20 | 0.53 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.53 |
| ▸ | GPBAR1 | Q8TDU6 | 6/20 | 0.52 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7532657 | 0.99 | PDE10A (0.58) | PDE10ACYSLTR1CYSLTR2GPBAR1ALOX5AP | |
| SCHEMBL8140420 | 0.83 | PDE10A (0.49) | PDE10ACYSLTR1CYSLTR2 | |
| SCHEMBL8801873 | 0.82 | MAOB (0.58) | PDE10ACYSLTR1CYSLTR2ALOX5AP | |
| SCHEMBL8129843 | 0.82 | CYSLTR1 (0.53) | PDE10ACYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL8801610 | 0.81 | MAOA (0.56) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL6421129 | 0.78 | MAOA (0.64) | — | |
| SCHEMBL8801952 | 0.78 | MAOA (0.62) | PDE10ACYSLTR1CYSLTR2GPBAR1ALOX5AP | |
| SCHEMBL10512475 | 0.77 | PDE10A (0.77) | PDE10ACYSLTR1CYSLTR2GPBAR1CYP1A2 | |
| SCHEMBL14302687 | 0.77 | PDE10A (0.44) | PDE10ACYSLTR1GPBAR1ALOX5APCYP1A2 | |
| SCHEMBL8801596 | 0.76 | PDE10A (0.53) | PDE10ACYSLTR1CYSLTR2GPBAR1ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1210343-A2 | BENZOIC ACID DERIVATIVES AND THEIR USE AS PPAR RECEPTOR AGONISTS | AstraZeneca AB (SE) | 2002-06-05 | — | — | EP | disclosed |
| WO-2001012187-A2 | BENZOIC ACID DERIVATIVES AND THEIR USE AS PPAR RECEPTOR AGONISTS | ASTRAZENECA AB (SE) | 2001-02-22 | — | — | WO | disclosed |