Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.58 |
| ▸ | MAOA | P21397 | 4/20 | 0.58 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.47 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8801610 | 0.92 | MAOA (0.56) | MAOBMAOACYSLTR1CYSLTR2 | |
| SCHEMBL7483348 | 0.82 | PDE10A (0.60) | CYSLTR1PDE10ACYSLTR2ALOX5AP | |
| SCHEMBL8800863 | 0.81 | MAOB (0.67) | MAOBMAOACYSLTR1FFAR1AKR1B1 | |
| Hydrochloric Acid SCHEMBL7532657 | 0.81 | PDE10A (0.58) | CYSLTR1PDE10ACYSLTR2ALOX5AP | |
| SCHEMBL8800859 | 0.80 | GPBAR1 (0.53) | MAOBMAOACYSLTR1FFAR1AKR1B1 | |
| SCHEMBL8140420 | 0.80 | PDE10A (0.49) | MAOBMAOACYSLTR1FFAR1AKR1B1 | |
| SCHEMBL6584542 | 0.79 | DRD2 (0.56) | MAOBMAOA | |
| SCHEMBL8140542 | 0.78 | MAOB (0.55) | MAOBMAOA | |
| SCHEMBL8801736 | 0.78 | CYSLTR1 (0.58) | MAOBMAOACYSLTR1CYSLTR2ALOX5AP | |
| SCHEMBL8801508 | 0.77 | CYSLTR1 (0.51) | CYSLTR1FFAR1AKR1B1PDE10ACYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799826-A1 | Heteroaryl substituted phenylene derivatives, their preparation and their use as leukotriene receptor antagonists | KOWA CO. LTD. (JP) | 1997-10-08 | — | — | EP | disclosed |