Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.43 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.39 |
| ▸ | PRCP | P42785 | 1/20 | 0.38 |
| ▸ | SCD | O00767 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7481567 | 0.88 | FFAR1 (0.45) | FFAR4AADATNPC1RAB9AFFAR1 | |
| SCHEMBL7484778 | 0.88 | FFAR1 (0.45) | FFAR4AADATNPC1RAB9AFFAR1 | |
| SCHEMBL7432425 | 0.87 | MEN1 (0.47) | NPC1RAB9AITGB1ITGA4 | |
| SCHEMBL7487553 | 0.87 | FFAR1 (0.42) | FFAR4AADATNPC1RAB9AFFAR1 | |
| SCHEMBL7433078 | 0.87 | FFAR1 (0.42) | FFAR4AADATNPC1RAB9AFFAR1 | |
| SCHEMBL7427408 | 0.86 | HRH3 (0.46) | AADATNPC1RAB9AFFAR1 | |
| SCHEMBL7431219 | 0.86 | RAB9A (0.42) | FFAR4AADATNPC1RAB9AFFAR1 | |
| SCHEMBL7433472 | 0.85 | CPT1A (0.42) | FFAR4AADATFFAR1RXRARXRB | |
| SCHEMBL7428579 | 0.84 | FFAR1 (0.43) | FFAR4NPC1RAB9AHCRTR1HCRTR2 | |
| SCHEMBL7583778 | 0.84 | FFAR1 (0.44) | FFAR4NPC1RAB9AHCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244656-A1 | NON-PEPTIDYL INHIBITORS OF VLA-4 DEPENDENT CELL BINDING USEFUL IN TREATING INFLAMMATORY, AUTOIMMUNE, AND RESPIRATORY DISEASES | Pfizer Products Inc. (US) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001051487-A1 | NON-PEPTIDYL INHIBITORS OF VLA-4 DEPENDENT CELL BINDING USEFUL IN TREATING INFLAMMATORY, AUTOIMMUNE, AND RESPIRATORY DISEASES | PFIZER PRODUCTS INC. (US) | 2001-07-19 | — | — | WO | disclosed |