Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.44 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 7/20 | 0.43 |
| ▸ | RAB9A | P51151 | 7/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7477926 | 0.87 | MAPT (0.50) | ITGB3ITGA2BITGA2NPC1RAB9A | |
| SCHEMBL7473771 | 0.85 | ITGB3 (0.49) | ITGB3ITGA2BITGA2NPC1RAB9A | |
| SCHEMBL7476748 | 0.83 | RORC (0.46) | ITGB3ITGA2BITGA2NPC1RAB9A | |
| SCHEMBL7478681 | 0.81 | MAPT (0.44) | ITGB3ITGA2BITGA2NPC1RAB9A | |
| SCHEMBL7429161 | 0.79 | MAPT (0.53) | ITGB3ITGA2BITGA2NPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL29803762 | 0.79 | RAB9A (0.56) | MAPKAPK2ITGB3ITGA2BNPC1RAB9A | |
| SCHEMBL24891825 | 0.77 | RAB9A (0.64) | ITGB3ITGA2BNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7479875 | 0.77 | ITGB3 (0.45) | MAPKAPK2ITGB3ITGA2BITGA2NPC1 | |
| SCHEMBL7477992 | 0.76 | RAB9A (0.55) | ITGB3ITGA2BITGA2NPC1RAB9A | |
| SCHEMBL7584355 | 0.74 | MAPT (0.54) | ITGB3ITGA2BNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885205-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 2002-11-27 | — | — | EP | disclosed |
| EP-0885205-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997031910-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1997-09-04 | — | — | WO | disclosed |