Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28787095 | 0.83 | TSHR (0.45) | TSHRSMN1; SMN2NAALAD2MAPT | |
| SCHEMBL748437 | 0.83 | TSHR (0.44) | TSHRSMN1; SMN2NAALAD2CTSSCA1 | |
| SCHEMBL12987008 | 0.80 | TSHR (0.40) | TSHRSMN1; SMN2NAALAD2CTSSKDM4C | |
| SCHEMBL23300631 | 0.77 | TSHR (0.33) | TSHRSMN1; SMN2MAPT | |
| SCHEMBL2837383 | 0.76 | CTSK (0.45) | TSHRSMN1; SMN2NAALAD2CTSSCA1 | |
| SCHEMBL1979477 | 0.76 | CTSK (0.45) | TSHRSMN1; SMN2NAALAD2CTSSCA1 | |
| SCHEMBL1979479 | 0.76 | CTSK (0.45) | TSHRSMN1; SMN2NAALAD2CTSSCA1 | |
| SCHEMBL5970504 | 0.72 | CTSS (0.57) | SMN1; SMN2CTSSCA1CA2 | |
| SCHEMBL1150932 | 0.72 | CTSS (0.57) | SMN1; SMN2CTSSCA1CA2 | |
| SCHEMBL5607969 | 0.70 | NAALAD2 (0.47) | TSHRSMN1; SMN2NAALAD2KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2430014-A1 | ANTIVIRAL COMPOUNDS | Gilead Sciences, Inc. (US) | 2012-03-21 | — | — | EP | disclosed |
| WO-2010132601-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2010-11-18 | — | — | WO | disclosed |