Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 8/20 | 0.34 |
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 2/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7484398 | 0.82 | CKS1B (0.42) | NR1H2DCTPP1ALDH1A1 | |
| SCHEMBL7484481 | 0.74 | DCTPP1 (0.47) | NR1H2DCTPP1HTTMETNR1H3 | |
| SCHEMBL7475885 | 0.73 | CHRM2 (0.37) | NR1H2DCTPP1ALDH1A1ADORA3 | |
| SCHEMBL7593155 | 0.71 | AAK1 (0.38) | NR1H2DCTPP1NR1H3ADORA3 | |
| SCHEMBL7481176 | 0.67 | CKS1B (0.45) | NR1H2NR1H3 | |
| SCHEMBL7965370 | 0.67 | BRD4 (0.44) | NR1H2ADORA3 | |
| SCHEMBL2860553 | 0.66 | MET (0.40) | DCTPP1HTTMETALDH1A1 | |
| SCHEMBL13426645 | 0.64 | HTT (0.49) | HTTMETALDH1A1 | |
| SCHEMBL9003358 | 0.63 | CTSD (0.43) | HTTALDH1A1CA12 | |
| SCHEMBL29510797 | 0.63 | CREBBP (0.44) | HTTMETALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946519-A1 | BENZAMIDE DERIVATIVES HAVING A VASOPRESSIN ANTAGONISTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998024771-A1 | BENZAMIDE DERIVATIVES HAVING A VASOPRESSIN ANTAGONISTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-11 | — | — | WO | disclosed |