Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TGM2 | P21980 | 2/20 | 0.49 |
| ▸ | CES1 | P23141 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 5/20 | 0.44 |
| ▸ | IDO1 | P14902 | 4/20 | 0.42 |
| ▸ | TDO2 | P48775 | 2/20 | 0.42 |
| ▸ | MGAT1 | P26572 | 1/20 | 0.42 |
| ▸ | MGAT3 | Q09327 | 1/20 | 0.42 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.42 |
| ▸ | PPOX | P50336 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | CBX7 | O95931 | 1/20 | 0.39 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.39 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.39 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7426938 | 0.78 | MAPT (0.55) | PGRMAPTTGM2CES1IDO1 | |
| SCHEMBL13732230 | 0.77 | PGR (0.58) | PGRHTR7IDO1 | |
| SCHEMBL2984831 | 0.72 | HTR7 (0.61) | PGRHTR7IDO1 | |
| SCHEMBL2976437 | 0.71 | HTR7 (0.64) | PGRHTR7 | |
| SCHEMBL31139641 | 0.69 | CES1 (0.77) | TGM2CES1IDO1TDO2PPOX | |
| SCHEMBL3521212 | 0.69 | PGR (1.00) | PGRHTR7 | |
| SCHEMBL8697033 | 0.68 | TGM2 (0.42) | PGRMAPTTGM2CES1IDO1 | |
| SCHEMBL8693444 | 0.68 | TGM2 (0.42) | PGRMAPTTGM2CES1IDO1 | |
| SCHEMBL8696547 | 0.68 | TGM2 (0.42) | PGRMAPTTGM2CES1IDO1 | |
| SCHEMBL7484503 | 0.68 | NSD2 (0.49) | PGRMAPTTGM2CES1HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697405-B1 | Substituted quinoline derivatives, process for their preparation and their use | AVENTIS PHARMA GMBH (DE) | 2002-08-14 | — | — | EP | disclosed |
| US-5798365-A | VIRICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-08-25 | — | — | US | disclosed |
| EP-0697405-A1 | Substituted quinoline derivatives, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-02-21 | — | — | EP | disclosed |