Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CRHBP | P24387 | 2/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10580640 | 0.81 | ALDH1A1 (0.41) | ALDH1A1TSHRTDP1GPR35CYP3A4 | |
| SCHEMBL8550097 | 0.80 | GPR35 (0.43) | ALDH1A1TSHRTDP1GPR35CYP3A4 | |
| SCHEMBL1979879 | 0.80 | PARP1 (0.41) | ALDH1A1TSHRTDP1GPR35CYP3A4 | |
| SCHEMBL29814297 | 0.80 | GPR35 (0.43) | ALDH1A1TSHRTDP1GPR35CYP3A4 | |
| SCHEMBL15427979 | 0.80 | ALDH1A1 (0.48) | ALDH1A1TSHRTDP1GPR35CYP3A4 | |
| SCHEMBL7084146 | 0.80 | MEN1 (0.46) | ALDH1A1TSHRCYP3A4MEN1KMT2A | |
| SCHEMBL8550301 | 0.80 | GPR35 (0.41) | ALDH1A1TSHRTDP1GPR35CYP3A4 | |
| SCHEMBL8117804 | 0.80 | ALDH1A1 (0.42) | ALDH1A1TSHRCYP3A4MEN1KMT2A | |
| SCHEMBL8545255 | 0.78 | PARP1 (0.43) | ALDH1A1CYP3A4MEN1KMT2ALMNA | |
| SCHEMBL29814344 | 0.78 | PARP1 (0.43) | ALDH1A1CYP3A4MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108329285-B | Method for synthesizing 2, 3-dihydrobenzofuran compound | 武汉大学 | 2019-12-10 | — | — | CN | disclosed |
| EP-0783499-B1 | BENZOFURAN DERIVATIVES AS TACHYKININ ANTAGONISTS | GLAXO GROUP LTD (GB) | 2002-10-23 | — | — | EP | disclosed |
| US-5935972-A | Benzofuran derivatives as tachykinin antagonists | GLAXO GROUP LIMITED (GB) | 1999-08-10 | — | — | US | disclosed |
| EP-0783499-A1 | BENZOFURAN DERIVATIVES AS TACHYKININ ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 1997-07-16 | — | — | EP | disclosed |
| WO-1995006645-A1 | BENZOFURAN DERIVATIVES AS TACHYKININ ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 1995-03-09 | — | — | WO | disclosed |