Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | GPR142 | Q7Z601 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | QPCT | Q16769 | 2/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7482093 | 0.87 | SMN1; SMN2 (0.38) | ALDH1A1SMN1; SMN2KDM4EGPR142CYP2D6 | |
| SCHEMBL7489818 | 0.84 | SMN1; SMN2 (0.35) | ALDH1A1SMN1; SMN2KDM4EQPCTL3MBTL1 | |
| SCHEMBL7829164 | 0.84 | HRH3 (0.35) | ALDH1A1KDM4E | |
| SCHEMBL7480136 | 0.83 | MAPT (0.33) | ALDH1A1SMN1; SMN2KDM4EQPCTL3MBTL1 | |
| SCHEMBL7482739 | 0.78 | CYP1A2 (0.32) | ALDH1A1SMN1; SMN2KDM4EQPCTL3MBTL1 | |
| SCHEMBL7514910 | 0.77 | CHRNB4 (0.33) | SMN1; SMN2GAA | |
| SCHEMBL7518500 | 0.76 | ALDH1A1 (0.31) | ALDH1A1L3MBTL1 | |
| SCHEMBL7484159 | 0.76 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2KDM4EL3MBTL1GAA | |
| SCHEMBL7827664 | 0.73 | ROCK2 (0.38) | KDM4E | |
| SCHEMBL7512987 | 0.70 | CNR1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0983268-B1 | AMIDINE DERIVATIVES AS INHIBITORS OF NITRIC OXIDE SYNTHASE | ASTRAZENECA AB (SE) | 2002-07-24 | — | — | EP | claimed |