Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 2/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.30 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7518500 | 0.97 | ALDH1A1 (0.31) | CHRNB4CHRNA3 | |
| SCHEMBL7515445 | 0.84 | L3MBTL3 (0.34) | — | |
| SCHEMBL7515962 | 0.82 | L3MBTL3 (0.35) | SMN1; SMN2 | |
| SCHEMBL7482093 | 0.81 | SMN1; SMN2 (0.38) | GAASMN1; SMN2 | |
| SCHEMBL7554137 | 0.81 | KDM4E (0.31) | — | |
| SCHEMBL7512824 | 0.81 | L3MBTL3 (0.35) | GAASMN1; SMN2 | |
| SCHEMBL7489818 | 0.77 | SMN1; SMN2 (0.35) | GAASMN1; SMN2 | |
| SCHEMBL7484693 | 0.77 | ALDH1A1 (0.32) | GAASMN1; SMN2 | |
| SCHEMBL7512987 | 0.76 | CNR1 (0.33) | — | |
| SCHEMBL7506634 | 0.76 | ALDH1A1 (0.40) | GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861250-B1 | AMIDINE AND ISOTHIOUREA DERIVATIVES AS INHIBITORS OF NITRIC OXIDE SYNTHASE | ASTRAZENECA AB (SE) | 2002-02-13 | — | — | EP | claimed |