Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | AVPR2 | P30518 | 15/20 | 0.32 |
| ▸ | AVPR1A | P37288 | 13/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7515445 | 0.85 | L3MBTL3 (0.34) | — | |
| SCHEMBL7515962 | 0.84 | L3MBTL3 (0.35) | — | |
| SCHEMBL7512824 | 0.83 | L3MBTL3 (0.35) | — | |
| SCHEMBL7550546 | 0.83 | HTR2A (0.33) | — | |
| SCHEMBL7510864 | 0.77 | — | — | |
| SCHEMBL7514910 | 0.76 | CHRNB4 (0.33) | — | |
| SCHEMBL7827664 | 0.76 | ROCK2 (0.38) | — | |
| SCHEMBL7518500 | 0.76 | ALDH1A1 (0.31) | — | |
| SCHEMBL7510035 | 0.75 | NPC1 (0.41) | AVPR2AVPR1A | |
| SCHEMBL7512428 | 0.75 | L3MBTL3 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861250-B1 | AMIDINE AND ISOTHIOUREA DERIVATIVES AS INHIBITORS OF NITRIC OXIDE SYNTHASE | ASTRAZENECA AB (SE) | 2002-02-13 | — | — | EP | claimed |