Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC1 | P33527 | 2/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SLC10A2 | Q12908 | 3/20 | 0.39 |
| ▸ | ACHE | P22303 | 3/20 | 0.38 |
| ▸ | CACNB4 | O00305 | 2/20 | 0.38 |
| ▸ | CACNA1A | O00555 | 2/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.38 |
| ▸ | CACNG3 | O60359 | 2/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.38 |
| ▸ | CACNB3 | P54284 | 2/20 | 0.38 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.38 |
| ▸ | CACNG7 | P62955 | 2/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.38 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.38 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.38 |
| ▸ | CACNG1 | Q06432 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7485921 | 0.91 | SLC10A2 (0.48) | ABCC1ABCG2ALDH1A1MAPTSLC10A2 | |
| SCHEMBL7491349 | 0.81 | ACHE (0.38) | ABCC1ABCG2ALDH1A1LMNAMAPT | |
| Diethylamine SCHEMBL7484722 | 0.81 | ABCG2 (0.51) | ABCC1ABCG2ALDH1A1LMNAMAPT | |
| SCHEMBL7490236 | 0.80 | CACNB4 (0.37) | ABCC1ABCG2ALDH1A1ACHECACNB4 | |
| SCHEMBL7489710 | 0.80 | KMT2A (0.42) | ACHECACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL7491371 | 0.80 | HTR1A (0.42) | ALDH1A1MAPTALOX15KDM4EMEN1 | |
| SCHEMBL7492373 | 0.78 | FGFR1 (0.36) | ABCC1ABCG2ALDH1A1LMNAMAPT | |
| SCHEMBL8139763 | 0.78 | KDM4E (0.42) | ALDH1A1MAPTSLC10A2ACHEPKM | |
| SCHEMBL7485972 | 0.78 | MAPT (0.53) | ABCG2ALDH1A1MAPTACHECACNB4 | |
| SCHEMBL7493208 | 0.78 | SLC10A2 (0.50) | ABCC1ABCG2ALDH1A1MAPTSLC10A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0791000-B1 | THIENOPYRIDINE OR THIENOPYRIMIDINE DERIVATIVES AND THEIR USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-10-02 | — | — | EP | claimed |