Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 5/20 | 0.42 |
| ▸ | HTR1B | P28222 | 5/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7489710 | 0.92 | KMT2A (0.42) | HTR1AADRA1DHTR1BADRA1AADRA1B | |
| SCHEMBL7489303 | 0.92 | CACNB4 (0.45) | HTR1AADRA1DHTR1BADRA1AADRA1B | |
| SCHEMBL7490401 | 0.88 | NT5E (0.46) | KDM4EMAPTALDH1A1BRD4HPGD | |
| SCHEMBL8317311 | 0.87 | P2RX3 (0.47) | MAPTNPSR1P2RX3 | |
| SCHEMBL7491349 | 0.85 | ACHE (0.38) | KDM4EMAPTALDH1A1HPGD | |
| SCHEMBL7490236 | 0.85 | CACNB4 (0.37) | KDM4EALDH1A1HPGD | |
| SCHEMBL7482329 | 0.84 | CACNB4 (0.44) | MAPTALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL7489312 | 0.84 | SLC10A2 (0.34) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL7677303 | 0.83 | NPSR1 (0.46) | KDM4EMAPTALDH1A1HPGDTSHR | |
| SCHEMBL7688241 | 0.82 | CACNB4 (0.44) | MAPTALDH1A1HPGDTSHRALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0791000-B1 | THIENOPYRIDINE OR THIENOPYRIMIDINE DERIVATIVES AND THEIR USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-10-02 | — | — | EP | claimed |