Fenfuram

Fenfuram

SCHEMBL748512

Cc1occc1C(=O)Nc1ccccc1.O=C(O)c1c(Cl)c(Cl)c(Cl)c(Cl)c1C(=O)Nc1cccc(Cl)c1Cl

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.54
ESR2 Q92731 1/20 0.54
POLB P06746 2/20 0.53
SMN1; SMN2 Q16637 6/20 0.52
NPC1 O15118 4/20 0.52
RAB9A P51151 4/20 0.52
HTT P42858 3/20 0.52
ALDH1A1 P00352 5/20 0.51
TP53 P04637 3/20 0.51
KMT2A Q03164 3/20 0.51
GAA P10253 2/20 0.51
MEN1 O00255 2/20 0.51
NFKB1 P19838 2/20 0.51
NFKB2 Q00653 2/20 0.51
RELA Q04206 2/20 0.51
LMNA P02545 3/20 0.47
MAPT P10636 1/20 0.47
GPR55 Q9Y2T6 1/20 0.46
HPGD P15428 1/20 0.45
PTGS2 P35354 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29360280 0.80 MEN1 (0.57) MAPK1POLBSMN1; SMN2NPC1RAB9A
SCHEMBL42567 0.80 MEN1 (0.57) MAPK1POLBSMN1; SMN2NPC1RAB9A
Fenfuram SCHEMBL18978 0.77 SMN1; SMN2 (0.73) MAPK1ESR2POLBSMN1; SMN2NPC1
SCHEMBL2761484 0.74 GAA (0.55) POLBSMN1; SMN2NPC1RAB9AHTT
SCHEMBL5454001 0.74 POLB (0.59) MAPK1ESR2POLBSMN1; SMN2NPC1
SCHEMBL7824641 0.73 MAPT (0.63) MAPK1POLBSMN1; SMN2ALDH1A1TP53
SCHEMBL8930036 0.73 MAPK1 (0.82) MAPK1ESR2POLBSMN1; SMN2NPC1
Mepronil SCHEMBL6051055 0.73 MAPT (0.45) MAPK1POLBSMN1; SMN2NPC1RAB9A
SCHEMBL7820722 0.73 CYP1A2 (0.57) MAPK1POLBSMN1; SMN2NPC1RAB9A
Fenfuram SCHEMBL11281245 0.72 KMT2A (0.76) MAPK1ESR2POLBSMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2031966-B1 LOW ODOR, LOW VOLATILITY SOLVENT FOR AGRICULTURAL CHEMICALS HUNTSMAN PETROCHEMICAL LLC (US) 2018-08-22 EP disclosed
US-20170360042-A1 MICRONIZED WOOD PRESERVATIVE FORMULATIONS IN ORGANIC CARRIERS ZHANG JUN (US) 2017-12-21 US disclosed
US-9775350-B2 Micronized wood preservative formulations in organic carriers KOPPERS PERFORMANCE CHEMICALS INC. (US) 2017-10-03 US disclosed
EP-2431430-B1 THE USE OF MICRONIZED WOOD PRESERVATIVE FORMULATIONS IN ORGANIC CARRIERS KOPPERS PERFORMANCE CHEMICALS INC (US) 2017-02-01 EP disclosed
US-8747908-B2 Micronized wood preservative formulations OSMOSE, INC. (US) 2014-06-10 US disclosed
CN-101453897-B Low odor, low volatility solvent for agricultural chemicals HUNTSMAN SPEC CHEM CORP 2013-10-30 CN disclosed
EP-1799776-B1 MICRONIZED WOOD PRESERVATIVE FORMULATIONS IN ORGANIC CARRIERS OSMOSE INC (US) 2013-01-02 EP disclosed
US-8298992-B2 Low odor, low volatility solvent for agricultural chemicals HUNTSMAN PETROCHEMICAL LLC (US) 2012-10-30 US disclosed
US-8168304-B2 Micronized wood preservative formulations comprising boron compounds OSMOSE, INC. (US) 2012-05-01 US disclosed
EP-2431430-A1 Micronized wood preservative formulations in organic carriers Osmose, Inc. (US) 2012-03-21 EP disclosed
US-20060112850-A1 Micronized wood preservative formulations in organic carriers OSMOSE UTILITIES SERVICES, INC. 2006-06-01 US disclosed
WO-2006053001-A2 POLYMER AND WATER REPELLENT COMPOSITIONS FOR WOOD PRODUCT DIMENSIONAL STABILITY OSMOSE, INC. (US) 2006-05-18 WO disclosed
US-20060100340-A1 Polymer and water repellent compositions for wood product dimensional stability OSMOSE, INC. 2006-05-11 US disclosed
WO-2006047126-A2 MICRONIZED WOOD PRESERVATIVE FORMULATIONS OSMOSE, INC. (US) 2006-05-04 WO disclosed
WO-2006044831-A2 NON-ALKALINE MICRONIZED WOOD PRESERVATIVE FORMULATIONS OSMOSE, INC. (US) 2006-04-27 WO disclosed
WO-2006044218-A2 MICRONIZED WOOD PRESERVATIVE FORMULATIONS IN ORGANIC CARRIERS OSMOSE, INC. (US) 2006-04-27 WO disclosed
US-20060086284-A1 Non-alkaline micronized wood preservative formulations OSMOSE, INC. 2006-04-27 US disclosed
US-20050249812-A1 Micronized organic preservative formulations OSMOSE, INC. 2005-11-10 US disclosed
WO-2005104841-A1 MICRONIZED ORGANIC PRESERVATIVE FORMULATIONS OSMOSE, INC. (US) 2005-11-10 WO disclosed
US-20050118280-A1 Micronized wood preservative formulations KOPPERS PERFORMANCE CHEMICALS NEW ZEALAND LIMITED (F/K/A OSMOSE NEW ZEALAND) (NZ) 2005-06-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050118280-A1 Micronized wood preservative formulations CD68, MME, BTD MAPK1 1984/4885ESR2 3332/4885POLB 2286/4885
US-20050249812-A1 Micronized organic preservative formulations MDN1, BTD, CD68 MAPK1 3259/4885ESR2 2645/4885POLB 428/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.