Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.51 |
| ▸ | TTR | P02766 | 1/20 | 0.51 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | AR | P10275 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29360280 | 0.86 | MEN1 (0.57) | MAPTKMT2AALDH1A1LMNAMEN1 | |
| SCHEMBL42567 | 0.86 | MEN1 (0.57) | MAPTKMT2AALDH1A1LMNAMEN1 | |
| SCHEMBL7820722 | 0.84 | CYP1A2 (0.57) | MAPTKMT2AALDH1A1LMNAMEN1 | |
| SCHEMBL7821493 | 0.82 | HPGD (0.58) | KMT2AALDH1A1LMNAMEN1HPGD | |
| SCHEMBL7821756 | 0.81 | POLB (0.64) | MAPTKMT2AALDH1A1LMNAMEN1 | |
| SCHEMBL2093177 | 0.79 | MAPT (0.71) | MAPTKMT2AALDH1A1LMNAMEN1 | |
| SCHEMBL7825161 | 0.78 | MAPT (0.68) | MAPTKMT2AALDH1A1LMNAMEN1 | |
| Iodide SCHEMBL30758631 | 0.77 | MAPT (0.84) | MAPTKMT2AALDH1A1LMNAMEN1 | |
| SCHEMBL7823201 | 0.76 | TAS1R3 (0.55) | TP53KMT2AALDH1A1LMNAMEN1 | |
| SCHEMBL8665346 | 0.75 | ALDH1A1 (0.54) | MAPTTP53KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |