Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 10/20 | 0.44 |
| ▸ | MAOA | P21397 | 7/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8194988 | 0.89 | MAOB (0.47) | RAB9AALDH1A1HPGDPOLBTSHR | |
| SCHEMBL7484704 | 0.85 | MAOB (0.45) | RAB9AALDH1A1HPGDPOLBTSHR | |
| SCHEMBL7485681 | 0.84 | KDM4E (0.50) | RAB9AALDH1A1HPGDPOLBHSD17B10 | |
| SCHEMBL8196371 | 0.77 | CELA1 (0.48) | RAB9AALDH1A1HPGDPOLBTSHR | |
| SCHEMBL7493197 | 0.76 | MEN1 (0.43) | RAB9AALDH1A1HPGDPOLBTSHR | |
| SCHEMBL13028007 | 0.71 | KDM4E (0.46) | ALDH1A1HPGDPOLBTSHRHSD17B10 | |
| SCHEMBL8807147 | 0.70 | ACHE (0.53) | KDM4EMAOBMEN1KMT2A | |
| SCHEMBL7493192 | 0.70 | KDM4E (0.45) | RAB9AALDH1A1HPGDPOLBHSD17B10 | |
| SCHEMBL7537705 | 0.70 | MAOB (0.39) | ALDH1A1HSD17B10MAOB | |
| SCHEMBL385093 | 0.70 | MAPT (0.51) | RAB9AALDH1A1HPGDHSP90AA1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1204644-A1 | SYNTHESIS OF SUBSTITUTED AMIDINES | ELI LILLY AND COMPANY (US) | 2002-05-15 | — | — | EP | disclosed |
| WO-2000078725-A1 | SYNTHESIS OF SUBSTITUTED AMIDINES | ELI LILLY AND COMPANY (US) | 2000-12-28 | — | — | WO | disclosed |
| WO-2000078724-A2 | IMIDAZOLINDERIVATIVES THEIR PREPARATION AND THEIR PHARMACEUTICAL USE | ELI LILLY AND COMPANY (US) | 2000-12-28 | — | — | WO | disclosed |
| US-6077829-A | COMPRISING BRAIN DERIVED NEUROTROPHIC FACTOR(BDNF), POLYOXYETHYLENE SORBITAN MONOOLEATE AS NONIONIC SURFACTANT, AND CARRIER; PREVENTS DENATURING AND POLYMERIZATION OF BDNF; STORAGE STABILITY | REGENERON PHARMACEUTICALS, INC. (US) | 2000-06-20 | — | — | US | disclosed |