Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.35 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.35 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.35 |
| ▸ | ALDH1B1 | P30837 | 1/20 | 0.35 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 3/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.34 |
| ▸ | ABCC1 | P33527 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7541979 | 0.87 | PGR (0.39) | ALDH1A1HSD17B10 | |
| SCHEMBL8218532 | 0.76 | NISCH (0.38) | NISCH | |
| SCHEMBL7536725 | 0.72 | NISCH (0.32) | NISCH | |
| SCHEMBL7543472 | 0.72 | KDM4E (0.36) | NISCH | |
| Hydrochloric Acid SCHEMBL8218663 | 0.72 | KDM4E (0.39) | NISCH | |
| SCHEMBL8194988 | 0.71 | MAOB (0.47) | MAOBALDH1A1HSD17B10ALDH1A2ALDH2 | |
| SCHEMBL8198539 | 0.71 | MC4R (0.49) | MAPK1NISCH | |
| Hydrochloric Acid SCHEMBL8203684 | 0.70 | MC4R (0.46) | MAPK1NISCH | |
| SCHEMBL7485171 | 0.70 | RAB9A (0.47) | MAOBALDH1A1HSD17B10 | |
| SCHEMBL6824821 | 0.69 | MC4R (0.43) | MAPK1NISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1204644-A1 | SYNTHESIS OF SUBSTITUTED AMIDINES | ELI LILLY AND COMPANY (US) | 2002-05-15 | — | — | EP | disclosed |
| WO-2000078725-A1 | SYNTHESIS OF SUBSTITUTED AMIDINES | ELI LILLY AND COMPANY (US) | 2000-12-28 | — | — | WO | disclosed |
| WO-2000078724-A2 | IMIDAZOLINDERIVATIVES THEIR PREPARATION AND THEIR PHARMACEUTICAL USE | ELI LILLY AND COMPANY (US) | 2000-12-28 | — | — | WO | disclosed |