Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | DRD5 | P21918 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16244844 | 0.93 | CCR1 (0.49) | CCR1KDM4EMEN1KMT2AOPRD1 | |
| SCHEMBL3278197 | 0.89 | APP (0.53) | CCR1KDM4EMEN1KMT2AAPP | |
| SCHEMBL7478597 | 0.88 | MEN1 (0.48) | CCR1KDM4EMEN1KMT2AOPRD1 | |
| SCHEMBL19212251 | 0.84 | OPRD1 (0.43) | OPRD1OPRK1HTR2AHTR7HRH1 | |
| SCHEMBL16245128 | 0.81 | DRD2 (0.48) | KMT2AOPRD1OPRK1APPDRD2 | |
| SCHEMBL6248104 | 0.81 | KMT2A (0.54) | MEN1KMT2AOPRD1OPRK1APP | |
| SCHEMBL3467822 | 0.79 | EPHX2 (0.53) | OPRD1OPRK1HRH1 | |
| SCHEMBL29087269 | 0.79 | CCR1 (0.59) | CCR1MEN1KMT2AOPRD1OPRK1 | |
| SCHEMBL23112637 | 0.78 | LMNA (0.43) | OPRD1OPRK1DRD2HTR1ADRD1 | |
| SCHEMBL23112776 | 0.78 | HRH2 (0.44) | MEN1KMT2AAPPHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1204665-A2 | CHEMOKINE RECEPTOR ANTAGONISTS AND METHODS OF USE THEREFOR | Millennium Pharmaceuticals, Inc. (US) | 2002-05-15 | — | — | EP | disclosed |
| WO-2001009138-A2 | CHEMOKINE RECEPTOR ANTAGONISTS AND METHODS OF USE THEREFOR | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2001-02-08 | — | — | WO | disclosed |