Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | TET3 | O43151 | 3/20 | 0.54 |
| ▸ | FBXL19 | Q6PCT2 | 3/20 | 0.54 |
| ▸ | CXXC5 | Q7LFL8 | 3/20 | 0.54 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.54 |
| ▸ | CXXC4 | Q9H2H0 | 3/20 | 0.54 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 2/20 | 0.48 |
| ▸ | TET1 | Q8NFU7 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HRH2 | P25021 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1447090 | 0.89 | OPRD1 (0.56) | KMT2ATET3FBXL19CXXC5KDM2B | |
| SCHEMBL9037444 | 0.86 | OPRD1 (0.51) | KMT2ATET3FBXL19CXXC5KDM2B | |
| SCHEMBL16244844 | 0.85 | CCR1 (0.49) | KMT2AMEN1OPRD1OPRK1APP | |
| SCHEMBL16245128 | 0.83 | DRD2 (0.48) | KMT2AOPRM1OPRD1OPRK1APP | |
| SCHEMBL8915729 | 0.82 | OPRM1 (0.53) | KMT2ATET3FBXL19CXXC5KDM2B | |
| SCHEMBL7478597 | 0.81 | MEN1 (0.48) | KMT2AMEN1OPRD1OPRK1APP | |
| SCHEMBL7485189 | 0.81 | CCR1 (0.45) | KMT2AMEN1OPRD1OPRK1APP | |
| SCHEMBL27472889 | 0.80 | OPRD1 (0.57) | OPRM1OPRD1OPRK1APPSMN1; SMN2 | |
| SCHEMBL8438413 | 0.79 | SMN1; SMN2 (0.55) | KMT2ATET3FBXL19CXXC5KDM2B | |
| SCHEMBL654813 | 0.78 | KMT2A (0.59) | KMT2ATET3FBXL19CXXC5KDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558577-A2 | SUBSTITUTED 4-PHENYL-PIPERIDIN-AMIDES AS TACHYKININ ANTAGONISTS AND SEROTONIN REPTAKE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2005-08-03 | — | — | EP | disclosed |
| WO-2004005256-A2 | SUBSTITUTED 4-PHENYL-PIPERIDIN-AMIDES AS TACHYKININ ANTAGONISTS AND SEROTONIN REPTAKE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2004-01-15 | — | — | WO | disclosed |